circRNA basic information
circBase ID: -
Name: hsa_circ_PUM1
Synonym: -
Host Gene: hsa-miR-1208
 
 
 
Disease basic information
DO ID:
684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: cell line, PDX
Sample type details: CCLM3, MHCC97H, MHCC97L, SK-HEP-1, HUH7, HEPG2
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: MAP3K2
Associated microRNA: hsa-miR-1208
Biological function: promote the proliferation, migration and invasion
Molecular mechanism: up-regulating the expression of MAP3K2
Survival: -
Supported No.:
1
Description:

circPUM1 could promote the development of HCC by up-regulating the expression of MAP3K2 via sponging miR-1208.

Other information
Title:

CircPUM1 promotes hepatocellular carcinoma progression through the miR-1208/MAP3K2 axis.

Journal: J Cell Mol Med
Published: 2020/12/16
PubMed ID: 33320435