circRNA basic information
circBase ID: -
Name: -
Synonym: hsa_circRNA_104348
Host Gene: hsa-miR-187-3p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Hep3B, SK-HEP-1, MHCC97L, MHCC97H, Huh7
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: RTKN2
Associated microRNA: hsa-miR-187-3p
Biological function: facilitated proliferation, migration, and invasion, meanwhile suppressed apoptosis
Molecular mechanism: targeting hsa-miR-187-3p/RTKN2 axis and activating Wnt/beta-catenin pathway
Survival: poor
Supported No.:
 1
Description:

circular RNA hsa_circRNA_104348 might function as a competing endogenous RNA (ceRNA) to promotes HCC progression by targeting miR-187-3p/RTKN2 axis and activating Wnt/beta-catenin pathway.
Other information
Title:

CircRNA hsa_circRNA_104348 promotes hepatocellular carcinoma progression through modulating miR-187-3p/RTKN2 axis and activating Wnt/beta-catenin pathway.

Journal: Cell Death Dis
Published: 2020/12/15
PubMed ID: 33311442