circRNA basic information
circBase ID: -
Name: hsa_circ_LRRK1
Synonym: -
Host Gene: hsa-miR-223-3p
 
 
 
Disease basic information
DO ID:
 10591
DO name: pre-eclampsia
Disease details: preeclampsia
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HTR-8/SVneo
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: PI3K/AKT signaling pathway
Associated microRNA: hsa-miR-223-3p
Biological function: suppress the proliferation, migration and invasion
Molecular mechanism: regulating the PI3K/AKT signaling pathway via targeting hsa-miR-223-3p
Survival: -
Supported No.:
 1
Description:

CircLRRK1 could suppress the proliferation, migration and invasion of trophoblast cells by regulating the PI3K/AKT signaling pathway via targeting miR-223-3p, suggesting that circLRRK1 might be a potential biomarker for the treatment of PE.
Other information
Title:

CircLRRK1 targets miR-223-3p to inhibit the proliferation, migration and invasion of trophoblast cells by regulating the PI3K/AKT signaling pathway.

Journal: Placenta
Published: 2020/12/15
PubMed ID: 33310596