circRNA basic information
circBase ID: -
Name: hsa_circ_XPO1
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: A549, SPC-A1, NCI-H460, NCI-H2126, NCI-H1703, NCI-H1299, 16-HBE
circRNA-disease information
Detected method:
Q
S
Detected method confidence High
Expression pattern:
UP
Associated gene: IGF2BP1
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Survival: poor
Supported No.:
1
Description:

circXPO1 could bind with IGF2BP1 and enhance CTNNB1 mRNA stability, and subsequently promote LUAD progression.

Other information
Title:

A novel circular RNA, circXPO1, promotes lung adenocarcinoma progression by interacting with IGF2BP1.

Journal: Cell Death Dis
Published: 2020/12/4
PubMed ID: 33268793