circRNA basic information
circBase ID: -
Name: -
Synonym: Circular RNA 100146
Host Gene: hsa-miR-149
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: cell line, PDX
Sample type details: T47D, MCF-7
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HMGA2
Associated microRNA: hsa-miR-149
Biological function: circRNA 100146 knockdown inhibited cell proliferation, promoted apoptosis, and suppressed migration and invasion in vitro and impeded tumor growth in vivo
Molecular mechanism: target the hsa-miR-149/HMGA2 axis
Survival: -
Supported No.:
 1
Description:

circRNA 100146 knockdown repressed proliferation, enhanced apoptosis, and hindered migration and invasion in SW620 and SW480 cells through targeting the miR-149/HMGA2 axis.
Other information
Title:

Circular RNA 100146 Promotes Colorectal Cancer Progression by the MicroRNA 149/HMGA2 Axis.

Journal: Mol Cell Biol
Published: 2020/12/2
PubMed ID: 33257506