circRNA basic information
circBase ID: -
Name: hsa_circ_GFRA1
Synonym: -
Host Gene: hsa-miR-149
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SK-HEP-1, Huh6, Huh7, HCCLM3
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-149
Biological function: promotes angiogenesis, cell proliferation and migration
Molecular mechanism: combining with hsa-miR-149
Survival: -
Supported No.:
 2
Description:

CircGFRA1 is highly expressed in HCC and its level is negatively correlated with miR-149 expression. CircGFRA1 can promote the proliferative, migration and angiogenic activity of HCC by binding miR-149.
Other information
Title:

Circular RNA circGFRA1 promotes angiogenesis, cell proliferation and migration of hepatocellular carcinoma by combining with miR-149.

Journal: Eur Rev Med Pharmacol Sci
Published: 2020/11/21
PubMed ID: 33215421