circRNA basic information
circBase ID: hsa_circ_0004370
Name: hsa_circ_PRRX1
Synonym: -
Host Gene: hsa-miR-665
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: SNU5, AGS
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: YWHAZ
Associated microRNA: hsa-miR-665
Biological function: circ-PRRX1 knockdown inhibited the viability, migration, and invasion and promoted apoptosis in GC cells
Molecular mechanism: targeting hsa-miR-665 to inhibit YWHAZ expression
Survival: -
Supported No.:
 2
Description:

Circ-PRRX1 knockdown suppressed GC development by targeting miR-665 to inhibit YWHAZ expression, and the potential molecular mechanism may provide a theoretical basis for GC therapy.
Other information
Title:

Circular RNA Paired-Related Homeobox 1 Promotes Gastric Carcinoma Cell Progression via Regulating MicroRNA-665/YWHAZ Axis.

Journal: Dig Dis Sci
Published: 2020/11/18
PubMed ID: 33201331