circRNA basic information
circBase ID: hsa_circ_0030998
Name: hsa_circ_LAMP1
Synonym: -
Host Gene: hsa-miR-558
 
 
 
Disease basic information
DO ID:
 1324
DO name: lung cancer
Disease details: lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: A549, H1299, H358, PC9
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-558
Biological function: suppress malignant phenotypes such as proliferation, migration, and invasion progression
Molecular mechanism: sponging hsa-miR-558
Survival: -
Supported No.:
 1
Description:

hsa_circ_0030998 can slow down the progression of lung cancer by targeting miR-558 and suppress malignant phenotypes such as proliferation, migration, and invasion progression of lung cancer cells. Therefore, we highlight that circ_0030998 could be a novel tumor suppressor of lung cancer.
Other information
Title:

A novel circular RNA, hsa_circ_0030998 suppresses lung cancer tumorigenesis and Taxol resistance by sponging miR-558.

Journal: Mol Oncol
Published: 2020/11/16
PubMed ID: 33190405