circRNA basic information
circBase ID: hsa_circ_0006916
Name: hsa_circ_HOMER1
Synonym: -
Host Gene: hsa-miR-599
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SRSF2
Associated microRNA: hsa-miR-599
Biological function: circ_0006916 expression was increased in HCC tissues and cell lines. circ_0006916 knockdown reduced cell viability, colony formation, migration and invasion and caused cell cycle arrest and apoptosis.
Molecular mechanism: regulate SRSF2 expression via hsa-miR-599
Survival: -
Supported No.:
 2
Description:

circ_0006916 knockdown represses the progression of HCC via regulating miR-599 and SRSF2.
Other information
Title:

Hsa_circ_0006916 Knockdown Represses the Development of Hepatocellular Carcinoma via Modulating miR-599/SRSF2 Axis.

Journal: Onco Targets Ther
Published: 2020/11/13
PubMed ID: 33177838