circRNA basic information
circBase ID: -
Name: hsa_circ_CBFB
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 409
DO name: liver disease
Disease details: liver injury
Species: human
Species details: human
Sample type: cell line
Sample type details: AML12
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: p66Shc
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
 1
Description:

p66Shc is a key regulator of APAP-induced liver injury that acts by triggering mitochondrial dynamics perturbation. circ-CBFB functions as a ceRNA to regulate p66Shc during APAP-induced liver injury, which may provide a potential therapeutic target.
Other information
Title:

circ-CBFB upregulates p66Shc to perturb mitochondrial dynamics in APAP-induced liver injury.

Journal: Cell Death Dis
Published: 2020/11/8
PubMed ID: 33159035