circRNA basic information
circBase ID: -
Name: hsa_circ_TMEM87A
Synonym: -
Host Gene: hsa-miR-142-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: MGC803, SGC7901, MKN45, BGC823, HGC27
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ULK1
Associated microRNA: hsa-miR-142-5p
Biological function: promotes cell proliferation and metastasis
Molecular mechanism: elevating ULK1 via sponging hsa-miR-142-5p
Survival: poor
Supported No.:
 1
Description:

circTMEM87A functions as an oncogene through the miR-142-5p/ULK1 axis in GC. CircTMEM87A might be a prognostic biomarker as well as a promising therapeutic target for GC.
Other information
Title:

Circular RNA TMEM87A promotes cell proliferation and metastasis of gastric cancer by elevating ULK1 via sponging miR-142-5p.

Journal: J Gastroenterol
Published: 2020/11/7
PubMed ID: 33155080