circRNA basic information
circBase ID: -
Name: hsa_circ_HECTD1
Synonym: -
Host Gene: hsa-miR-133b
 
 
 
Disease basic information
DO ID:
6713
DO name: cerebrovascular disease
Disease details: ischemic stroke
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: TRAF3
Associated microRNA: hsa-miR-133b
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
3
Description:

circ-HECTD1 knockdown inhibited the expression of TRAF3 by targeting miR-133b, thereby attenuating neuronal injury caused by cerebral ischemia.

Other information
Title:

Downregulation of circular RNA HECTD1 induces neuroprotection against ischemic stroke through the microRNA-133b/TRAF3 pathway.

Journal: Life Sci
Published: 2020/11/6
PubMed ID: 33148417