circRNA basic information
circBase ID: hsa_circ_0001445
Name: hsa_circ_SMARCA5
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
11476
DO name: osteoporosis
Disease details: osteoporosis
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Survival: -
Supported No.:
1
Description:

The expression levels of hsa_circ_0001445 in plasma were much lower in OPO patients compared with OPE patients and healthy controls. Its expression was positively correlated with the T-score and was negatively correlated with beta-isomerized C-terminal telopeptides (beta-CTx). It could distinguish OPE or/and OPO patients from healthy controls. Moreover, its expression was significantly upregulated in the plasma of OPO patients after anti-osteoporotic treatment.

Other information
Title:

Circular RNA hsa_circ_0001445 in plasma as a novel biomarker for osteoporosis in postmenopausal women.

Journal: Biomark Med
Published: 2020/11/4
PubMed ID: 33140658