circRNA basic information
circBase ID: hsa_circ_0032821
Name: hsa_circ_CEP128
Synonym: -
Host Gene: hsa-miR-515-5p
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: HGC-27, AGS
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SOX9
Associated microRNA: hsa-miR-515-5p
Biological function: boost OXA resistance, proliferation, migration, and invasion in OXA-sensitive GC cells
Molecular mechanism: regulating SOX9 via hsa-miR-515-5p
Survival: -
Supported No.:
 3
Description:

Exosomal circ_0032821 boosted OXA resistance of GC cells partly by the miR-515-5p/SOX9 axis, hinting a promising therapeutic target for GC treatment.
Other information
Title:

Circular RNA circ_0032821 contributes to oxaliplatin (OXA) resistance of gastric cancer cells by regulating SOX9 via miR-515-5p.

Journal: Biotechnol Lett
Published: 2020/10/31
PubMed ID: 33123829