circRNA basic information
circBase ID: hsa_circ_0006168
Name: hsa_circ_CNOT6L
Synonym: -
Host Gene: hsa-miR-100
 
 
 
Disease basic information
DO ID:
 3748
DO name: esophagus squamous cell carcinoma
Disease details: esophageal squamous cell carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: ESCC cell lines (TE13, ECA109, Kyse150, Kyse450, Kyse510), normal esophageal cell line (Het-1A)
circRNA-disease information
Detected method:
M
Detected method confidence Low
Expression pattern:
UP
Associated gene: mTOR
Associated microRNA: hsa-miR-100
Biological function: promote the proliferation, migration and invasion
Molecular mechanism: regulate the expression of Mammalian Target of Rapamycin (mTOR) by sponging microRNA-100 (hsa-miR-100
Survival: -
Supported No.:
 3
Description:

hsa_circ_0006168 can promote ESCC proliferation, migration and invasion through the competing endogenous RNA (ceRNA) mechanism, which has been first confirmed in our results.
Other information
Title:

hsa_circ_0006168 sponges miR-100 and regulates mTOR to promote the proliferation, migration and invasion of esophageal squamous cell carcinoma.

Journal: Biomed Pharmacother
Published: 2019/6/24
PubMed ID: 31229921