circRNA basic information
circBase ID: -
Name: hsa_circ_UGGT2
Synonym: -
Host Gene: hsa-miR-526b-5p
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: HuH-7, SK-HEP-1
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: RAB1A
Associated microRNA: hsa-miR-526b-5p
Biological function: CircUGGT2 silencing suppressed tumor growth in vivo and curbed proliferation, colony formation, cell cycle progression, migration, and invasion of HCC cells in vitro
Molecular mechanism: regulated RAB1A expression via competitively binding to hsa-miR-526b-5p
Survival: -
Supported No.:
 2
Description:

CircUGGT2 silencing inhibited HCC development via modulating the miR-526b-5p/RAB1A axis, providing a possible target for HCC treatment.
Other information
Title:

CircRNA circUGGT2 Contributes to Hepatocellular Carcinoma Development via Regulation of the miR-526b-5p/RAB1A Axis.

Journal: Cancer Manag Res
Published: 2020/10/30
PubMed ID: 33116877