circRNA basic information
circBase ID: hsa_circ_0003645
Name: hsa_circ_C16orf62
Synonym: -
Host Gene: hsa-miR-139-3p
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: MCF-7 cells, MDA-MB-231
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HMGB1
Associated microRNA: hsa-miR-139-3p
Biological function: promoted the breast cancer cells progression and positively
Molecular mechanism: functions as a ceRNA for hsa-miR-139-3p, which could upregulate HMGB1
Survival: -
Supported No.:
 1
Description:

Circ_0003645 functions as a ceRNA for miR-139-3p, which could upregulate HMGB1 and further promote cell proliferation in breast cancer.
Other information
Title:

Hsa_circ_0003645 Promotes Breast Cancer Progression by Regulating miR-139-3p/HMGB1 Axis.

Journal: Onco Targets Ther
Published: 2020/10/30
PubMed ID: 33116616