circRNA basic information
circBase ID: hsa_circ_0009143
Name: hsa_circ_PVT1
Synonym: -
Host Gene: hsa-miR-1286
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HUCEC, C33A, HCC-94, Hela, CASKI, C33A, HCC-94, Hela, CASKI
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-1286
Biological function: induced migration and invasion of cervical cancer cells, which would result in the promotion of pulmonary metastasis
Molecular mechanism: targeting hsa-miR-1286
Survival: -
Supported No.:
 1
Description:

circRNA_PVT1 can induce EMT of cervical cancer cells via targeting miR-1286 by exosome pathway, which can be a novel mechanism of cervical cancer progression.
Other information
Title:

Circular RNA circ_PVT1 induces epithelial-mesenchymal transition to promote metastasis of cervical cancer.

Journal: Aging (Albany NY)
Published: 2020/10/29
PubMed ID: 33109773