circRNA basic information
circBase ID: hsa_circ_0058124
Name: -
Synonym: circ_0058124
Host Gene: hsa-miR-370-3p
 
 
 
Disease basic information
DO ID:
 3969
DO name: thyroid gland papillary carcinoma
Disease details: papillary thyroid cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: IHH-4, TPC-1
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: LMO4
Associated microRNA: hsa-miR-370-3p
Biological function: Circ_0058124 knockdown inhibited viability, colony formation, migration and invasion and promoted apoptosis of PTC cells
Molecular mechanism: mediating the hsa-miR-370-3p/LMO4 axis
Survival: -
Supported No.:
 2
Description:

Circ_0058124 promoted the development of PTC by mediating the miR-370-3p/LMO4 axis, and circ_0058124, functioned as an oncogene in PTC, might be used as a promising biomarker for PTC diagnosis and treatment.
Other information
Title:

Circ_0058124 Aggravates the Progression of Papillary Thyroid Carcinoma by Activating LMO4 Expression via Targeting miR-370-3p.

Journal: Cancer Manag Res
Published: 2020/10/17
PubMed ID: 33061633