circRNA basic information
circBase ID: hsa_circ_0084927
Name: hsa_circ_ESRP1
Synonym: -
Host Gene: hsa-miR-634
 
 
 
Disease basic information
DO ID:
 4362
DO name: cervical cancer
Disease details: cervical cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: Hela, SiHa, CaSki, C-33A
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: TPD52
Associated microRNA: hsa-miR-634
Biological function: Hsa_circ_0084927 silencing reduced tumor growth in vivo and induced cell cycle arrest, apoptosis, and curbed proliferation, colony formation, migration, and invasion of CC cells in vitro
Molecular mechanism: upregulating TPD52 via sponging hsa-miR-634
Survival: -
Supported No.:
 3
Description:

Hsa_circ_0084927 accelerated CC advancement via upregulating TPD52 via sponging miR-634, offering a new evidence to support hsa_circ_0084927 as a promising target for CC treatment.
Other information
Title:

Hsa_circ_0084927 Regulates Cervical Cancer Advancement via Regulation of the miR-634/TPD52 Axis.

Journal: Cancer Manag Res
Published: 2020/10/17
PubMed ID: 33061631