circRNA basic information
circBase ID: hsa_circ_0028171
Name: -
Synonym: circ_0028171
Host Gene: hsa-miR-218-5p
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HOB1, MG63, Saos-2, U2OS,143B
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: IKBKB
Associated microRNA: hsa-miR-218-5p
Biological function: enhanced cell proliferation, migration and invasion abilities
Molecular mechanism: served as a sponge of hsa-miR-218-5p to increase IKBKB expression
Survival: -
Supported No.:
 1
Description:

circ_0028171 might promote the malignant behavior of OS tissues through miR-218-5p/IKBKB axis, which could be a potential novel marker for early diagnosis of OS.
Other information
Title:

The novel circ_0028171/miR-218-5p/IKBKB axis promotes osteosarcoma cancer progression.

Journal: Cancer Cell Int
Published: 2020/10/13
PubMed ID: 33041665