circRNA basic information
circBase ID:
-
Name:
hsa_circ_DENND2A
Synonym:
-
Host Gene:
hsa-miR-34a
Disease basic information
DO ID:
3908
DO name:
lung non-small cell carcinoma
Disease details:
non-small cell lung cancer
Species:
human
Species details:
human
Sample type:
tissue, cell line
Sample type details:
A549, H1299
circRNA-disease information
Detected method:
Q
Detected method confidence
High
Expression pattern:
DN
Associated gene:
CCNE1
Associated microRNA:
hsa-miR-34a
Biological function:
circDENND2A knockdown suppressed cell growth via inducing cell cycle arrest and apoptosis and inhibited cell migration and invasion
Molecular mechanism:
directly bind to hsa-miR-34a, promoting CCNE1 expression
Survival:
-
Supported No.:
1
Description:
CircDENND2A Promotes Non-small Cell Lung Cancer Progression via Regulating MiR-34a/CCNE1 Signaling.
Other information
Title:
CircDENND2A Promotes Non-small Cell Lung Cancer Progression via Regulating MiR-34a/CCNE1 Signaling.
Journal:
Front Genet
Published:
2020/10/10
PubMed ID:
33033491