circRNA basic information
circBase ID: hsa_circ_0005556
Name: hsa_circ_NBAS
Synonym: -
Host Gene: hsa-miR-4270
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: HGC-27, MKN-28, MGC-803
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: MMP19
Associated microRNA: hsa-miR-4270
Biological function: the downregulation of hsa_circ_0005556 significantly inhibited proliferation, migration, and invasion of gastric cancer cells
Molecular mechanism: hsa_circ_0005556/hsa-miR-4270/MMP19 axis
Survival: -
Supported No.:
 3
Description:

Our study shows that the hsa_circ_0005556/miR-4270/MMP19 axis is involved in proliferation, migration, and invasion of gastric cancer cells through the competing endogenous RNA (ceRNA) mechanism.
Other information
Title:

Circular RNA hsa_circ_0005556 Accelerates Gastric Cancer Progression by Sponging miR-4270 to Increase MMP19 Expression.

Journal: J Gastric Cancer
Published: 2020/10/8
PubMed ID: 33024586