circRNA basic information
circBase ID: -
Name: hsa_circ_LPHN2
Synonym: circRNA_100269
Host Gene: hsa-miR-630
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human colorectal cancer cell lines (AGS, MKN28, MKN45, BGC823, MGC803, SGC7901, GES1)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-630
Biological function: suppress cell proliferation, migration, and invasion
Molecular mechanism: targeting hsa-miR-630
Survival: better
Supported No.:
 1
Description:

Overexpressing the circRNA_100269 plasmid inhibited cell proliferation. circRNA_100269 and miR-630 comprise a novel pathway that regulates proliferation of GC cells.
Other information
Title:

CircRNA_100269 is downregulated in gastric cancer and suppresses tumor cell growth by targeting miR-630.

Journal: Aging (Albany NY)
Published: 2017/6/29
PubMed ID: 28657541