circRNA basic information
circBase ID: -
Name: hsa_circ_C16orf62
Synonym: -
Host Gene: hsa-miR-421
 
 
 
Disease basic information
DO ID:
 10534
DO name: stomach cancer
Disease details: gastric cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: MKN-74, HGC-27, AGS
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: Tubulin beta-2A Chain (TUBB2A)
Associated microRNA: hsa-miR-421
Biological function: repressed proliferation, migration, and invasion
Molecular mechanism: by the hsa-miR-421/TUBB2A axis
Survival: -
Supported No.:
 1
Description:

circ_C16orf62 impeded proliferation, migration, and invasion in vitro and retarded tumor growth in vivo by the miR-421/TUBB2A axis in GC, providing a potential therapeutic strategy for patients with GC.
Other information
Title:

Circular RNA circ_C16orf62 Suppresses Cell Growth in Gastric Cancer by miR-421/Tubulin beta-2A Chain (TUBB2A) Axis.

Journal: Med Sci Monit
Published: 2020/10/3
PubMed ID: 33006960