circRNA basic information
circBase ID: hsa_circ_0000284
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: hsa-miR-124
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: SW1783, U373
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: CCND2
Associated microRNA: hsa-miR-124
Biological function: down-regulation of circHIPK3 significantly inhibited the proliferation, migration and invasion of glioma cells
Molecular mechanism: absorb hsa-miR-124 and promoted CCND2 expression
Survival: -
Supported No.:
 7
Description:

circHIPK3 had carcinogenic effects by regulating the expression of CCND2 in glioma by sponging miR-124. These findings provided favorable evidence to reveal the role of circHIPK3 in the development of gliomas.
Other information
Title:

Circular RNA CircHIPK3 Elevates CCND2 Expression and Promotes Cell Proliferation and Invasion Through miR-124 in Glioma.

Journal: Front Genet
Published: 2020/10/3
PubMed ID: 33005182