circRNA basic information
circBase ID: hsa_circ_0003496
Name: hsa_circ_UBAP2
Synonym: -
Host Gene: hsa-miR-370
 
 
 
Disease basic information
DO ID:
 3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: cell line
Sample type details: KHOS, MG63
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: KLF12
Associated microRNA: hsa-miR-370
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 5
Description:

Our present work suggested that the knockdown of circ_0003496 suppressed OS progression and enhanced DXR sensitivity at least partially through modulating KLF12 expression via functioning as a miR-370 sponge, highlighting new opportunities for OS management.
Other information
Title:

Circular RNA hsa_circ_0003496 Contributes to Tumorigenesis and Chemoresistance in Osteosarcoma Through Targeting (microRNA) miR-370/Kruppel-Like Factor 12 Axis.

Journal: Cancer Manag Res
Published: 2020/9/29
PubMed ID: 32982419