circRNA basic information
circBase ID: -
Name: hsa_circ_ZNF609
Synonym: -
Host Gene: hsa-miR-338-3p
 
 
 
Disease basic information
DO ID:
 9261
DO name: nasopharynx carcinoma
Disease details: nasopharyngeal carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: HNE-3, C666-1, 5-8F, SUNE1
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HRAS
Associated microRNA: hsa-miR-338-3p
Biological function: promotes cell proliferation, migration, invasion, and glycolysis
Molecular mechanism: regulating HRAS via hsa-miR-338-3p
Survival: -
Supported No.:
 5
Description:

circZNF609 acted as a competing endogenous RNA of miR-338-3p to regulate HRAS. CircZNF609 knockdown suppressed cell tumorigenesis in NPC via regulating miR-338-3p/HRAS axis, suggesting a novel therapeutic strategy for NPC.
Other information
Title:

CircZNF609 promotes cell proliferation, migration, invasion, and glycolysis in nasopharyngeal carcinoma through regulating HRAS via miR-338-3p.

Journal: Mol Cell Biochem
Published: 2020/9/25
PubMed ID: 32970285