circRNA basic information
circBase ID: hsa_circ_0001649
Name: hsa_circ_SHPRH
Synonym: -
Host Gene: hsa-miR-338-5p, hsa-miR-647, hsa-miR-942
 
 
 
Disease basic information
DO ID:
3347
DO name: osteosarcoma
Disease details: osteosarcoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: MG63, U2OS, HOS, Saos-2
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: -
Associated microRNA: hsa-miR-338-5p, hsa-miR-647, hsa-miR-942
Biological function: suppress cell proliferation, induce apoptosis and inhibit STAT pathway
Molecular mechanism: worked as a sponge to absorb hsa-miR-338-5p, hsa-miR-647 and hsa-miR-942
Survival: -
Supported No.:
1
Description:

circ_0001649 worked as a sponge to absorb miR-338-5p, miR-647 and miR-942 to suppress cell proliferation, induce apoptosis and inhibit STAT pathway. Circ_0001649 suppressed OS cell proliferation and STAT pathway and induced apoptosis through sponging miR-338-5p, miR-647 and miR-942.

Other information
Title:

Circular RNA hsa_circ_0001649 suppresses the growth of osteosarcoma cells via sponging multiple miRNAs.

Journal: Cell Cycle
Published: 2020/9/22
PubMed ID: 32954926