circRNA basic information
circBase ID: hsa_circ_0000079
Name: hsa_circ_USP1
Synonym: -
Host Gene: -
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: BEAS-2B, HBE, A549, H460, A549/DDP, H460/DDP
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: FXR1/PRCKI Complex
Associated microRNA: -
Biological function: -
Molecular mechanism: -
Survival: better
Supported No.:
 1
Description:

circ_0000079 might inhibit cell invasion and drug resistance in NSCLC by interrupting the formation of the FXR1/PRCKI complex by interacting with FXR1, and circ_0000079 could act as a potential biomarker and therapeutic target for NSCLC.
Other information
Title:

Circ_0000079 Decoys the RNA-Binding Protein FXR1 to Interrupt Formation of the FXR1/PRCKI Complex and Decline Their Mediated Cell Invasion and Drug Resistance in NSCLC.

Journal: Cell Transplant
Published: 2020/9/22
PubMed ID: 32951448