circRNA basic information
circBase ID: hsa_circ_0086720
Name: hsa_circ_UBAP2
Synonym: -
Host Gene: hsa-miR-375
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: cell line, PDX
Sample type details: A549, H1299
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SPIN1
Associated microRNA: hsa-miR-375
Biological function: Circ_0086720 knockdown strengthens the radiosensitivity
Molecular mechanism: mediating the hsa-miR-375/SPIN1 axis
Survival: -
Supported No.:
 1
Description:

circ_0086720 downregulation enhanced the sensitivity of NSCLC to radiation by regulating the miR-375/SPIN1 axis, contributing to the improvement of the radiotherapies in NSCLC.
Other information
Title:

Circ_0086720 knockdown strengthens the radiosensitivity of non-small cell lung cancer via mediating the miR-375/SPIN1 axis.

Journal: Neoplasma
Published: 2020/9/18
PubMed ID: 32940043