circRNA basic information
circBase ID: -
Name: hsa_circ_PRKCB
Synonym: -
Host Gene: hsa-miR-339-5p
 
 
 
Disease basic information
DO ID:
 936
DO name: brain disease
Disease details: ischemia reperfusion injury
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Caco-2
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: p66Shc
Associated microRNA: hsa-miR-339-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 1
Description:

Our findings reveal a crucial role for the circ-PRKCB/miR-339-5p/p66Shc signaling pathway in regulating oxidative stress in the I/R intestine. This pathway may be a potential therapeutic target for intestinal I/R injury.
Other information
Title:

circ-PRKCB acts as a ceRNA to regulate p66Shc-mediated oxidative stress in intestinal ischemia/reperfusion.

Journal: Theranostics
Published: 2020/9/16
PubMed ID: 32929374