circRNA basic information
circBase ID: hsa_circ_0000376
Name: hsa_circ_PRH1-PRR4
Synonym: -
Host Gene: hsa-miR-1182
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: H522, H1975
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: NOVA2
Associated microRNA: hsa-miR-1182
Biological function: silencing of circ_0000376 could inhibit the glycolysis, viability, migration, and invasion of hypoxia-induced NSCLC cells.
Molecular mechanism: sponge hsa-miR-1182, and hsa-miR-1182 could target NOVA2
Survival: poor
Supported No.:
 4
Description:

Circ_0000376 promoted NSCLC progression by regulating the miR-1182/NOVA2 axis, suggesting that circ_0000376 might be a potential biomarker for NSCLC treatment.
Other information
Title:

Circ_0000376, a Novel circRNA, Promotes the Progression of Non-Small Cell Lung Cancer Through Regulating the miR-1182/NOVA2 Network.

Journal: Cancer Manag Res
Published: 2020/9/15
PubMed ID: 32922073