circRNA basic information
circBase ID: hsa_circ_0082374
Name: hsa_circ_CPA4
Synonym: -
Host Gene: hsa-miR-326
 
 
 
Disease basic information
DO ID:
 0060108
DO name: brain glioma
Disease details: glioma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human glioma cell lines (A172, BT325, LN229, U251, SHG44), normal human astrocytes (HA1800)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SIRT1
Associated microRNA: hsa-miR-326
Biological function: Knockdown of circ0082374 inhibits cell viability, migration, invasion and glycolysis
Molecular mechanism: regulating hsa-miR-326 and SIRT1
Survival: -
Supported No.:
 3
Description:

silence of circ0082374 repressed the viability, migration, invasion and glycolysis in glioma cells by regulating miR-326 and SIRT1 in a ceRNA mechanism, providing a new mechanism for the pathogenesis of glioma.
Other information
Title:

Knockdown of circ0082374 inhibits cell viability, migration, invasion and glycolysis in glioma cells by miR-326/SIRT1.

Journal: Brain Res
Published: 2020/9/9
PubMed ID: 32896523