circRNA basic information
circBase ID: hsa_circ_0007142
Name: hsa_circ_DOCK1
Synonym: -
Host Gene: hsa-miR-455-5p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: SGK1
Associated microRNA: hsa-miR-455-5p
Biological function: Circ_0007142 silencing promoted cell apoptosis and inhibited cell proliferation, migration and invasion
Molecular mechanism: Circ_0007142/hsa-miR-455-5p/SGK1 axis
Survival: -
Supported No.:
 4
Description:

Circ_0007142/miR-455-5p/SGK1 axis regulated cell proliferation, apoptosis, migration and invasion of CRC cells, providing a probable therapy target for CRC.
Other information
Title:

Circular RNA circ_0007142 regulates cell proliferation, apoptosis, migration and invasion via miR-455-5p/SGK1 axis in colorectal cancer.

Journal: Anticancer Drugs
Published: 2020/9/6
PubMed ID: 32889894