circRNA basic information
circBase ID: hsa_circ_0000284
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: hsa-miR-185
 
 
 
Disease basic information
DO ID:
 557
DO name: kidney disease
Disease details: diabetic nephropathy
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Rat MCs
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-185
Biological function: down-regulation of circHIPK3 inhibited cell proliferation
Molecular mechanism: sponging hsa-miR-185
Survival: -
Supported No.:
 3
Description:

circHIPK3 exhibits a promotive function in DN by sponging miR-185 and this evidence suggests that circHIPK3 might be a biomarker or therapeutic target for DN.
Other information
Title:

Circular RNA HIPK3 exacerbates diabetic nephropathy and promotes proliferation by sponging miR-185.

Journal: Gene
Published: 2020/9/6
PubMed ID: 32889056