circRNA basic information
circBase ID: hsa_circ_0015756
Name: hsa_circ_CFH
Synonym: -
Host Gene: hsa-miR-610
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: HCC cell lines (SNU-387, Huh7), immortalized human hepatocytes (THLE-2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: FGFR1
Associated microRNA: hsa-miR-610
Biological function: Circ_0015756 downregulation impaired HCC cell viability, colony formation capacity, invasion and migration, induced cell cycle arrest and apoptosis, and inhibited tumor growth in vivo
Molecular mechanism: Sponging hsa-miR-610
Survival: -
Supported No.:
 3
Description:

Circ_0015756 played its tumorigenic properties in HCC by activating FGFR1 via sponging miR-610, and circ_0015756 was expected to be a vital indicator in HCC diagnosis and treatment.
Other information
Title:

Circ_0015756 Aggravates Hepatocellular Carcinoma Development by Regulating FGFR1 via Sponging miR-610.

Journal: Cancer Manag Res
Published: 2020/9/5
PubMed ID: 32884351