circRNA basic information
circBase ID: hsa_circ_0000291
Name: hsa_circ_CD44
Synonym: -
Host Gene: hsa-miR-326
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human BC cell lines (MCF_7, MDA_MB_468, MDA_MB_231, BT_20, BT_474), normal mammary epithelial cell lines (MCF_10A)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ETS1
Associated microRNA: hsa-miR-326
Biological function: promoted BC cell proliferation, migration and invasion
Molecular mechanism: decoy hsa-miR-326 and in turn upregulate the expression of ETS1
Survival: -
Supported No.:
 2
Description:

Circ_0000291 is the novel oncogenic circRNA and promotes BC progression via modulating the miR-326/ETS1 axis.
Other information
Title:

The circRNA circ_0000291 acts as a sponge of microRNA 326 to regulate E26 transformation-specific sequence-1 expression and promote breast cancer progression.

Journal: Pathol Int
Published: 2020/9/2
PubMed ID: 32869935