circRNA basic information
circBase ID: hsa_circ_0007031
Name: hsa_circ_TUBGCP3
Synonym: -
Host Gene: hsa-miR-133b
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: CRC cell lines (HCT116, SW480)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: ABCC5
Associated microRNA: hsa-miR-133b
Biological function: Circ_0007031 knockdown repressed CRC cell proliferation, migration and invasion and enhanced 5-FU sensitivity
Molecular mechanism: sponging hsa-miR-133b
Survival: -
Supported No.:
 4
Description:

Our current work had led to the identification of circ_0007031 knockdown that repressed CRC cell malignant progression and enhanced 5-FU sensitivity via regulating ABCC5 expression by sponging miR-133b.
Other information
Title:

Circ_0007031 enhances tumor progression and promotes 5-fluorouracil resistance in colorectal cancer through regulating miR-133b/ABCC5 axis.

Journal: Cancer Biomark
Published: 2020/9/1
PubMed ID: 32865180