circRNA basic information
circBase ID: hsa_circ_0000517
Name: hsa_circ_RPPH1
Synonym: -
Host Gene: hsa-miR-326
 
 
 
Disease basic information
DO ID:
 684
DO name: hepatocellular carcinoma
Disease details: hepatocellular carcinoma
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: normal liver cell line (THLE-2), hepatocellular carcinoma cell lines (HCCLM3, Huh7)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: IGF1R
Associated microRNA: hsa-miR-326
Biological function: circ_0000517 knockdown suppressed cell viability, colony formation, migration, invasion and glycolysis
Molecular mechanism: modulating hsa-miR-326 and IGF1R
Survival: -
Supported No.:
 6
Description:

Circ_0000517 knockdown repressed hepatocellular carcinoma development in vitro and in vivo by modulating miR-326 and IGF1R.
Other information
Title:

Circular RNA circ_0000517 regulates hepatocellular carcinoma development via miR-326/IGF1R axis.

Journal: Cancer Cell Int
Published: 2020/8/31
PubMed ID: 32863763