circRNA basic information
circBase ID: -
Name: hsa_circ_MAT2B
Synonym: -
Host Gene: hsa-miR-610
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: human CRC cell lines (NCM460, HT29, HCT116, HCT8, SW480, DLD1, Caco2)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: E2F1
Associated microRNA: hsa-miR-610
Biological function: promoted CRC proliferation
Molecular mechanism: regulating the hsa-miR-610/E2F1 axis
Survival: -
Supported No.:
 1
Description:

circMAT2B promoted CRC proliferation by regulating the miR-610/E2F1 axis, which may serve as a potential therapeutic target for CRC treatment.
Other information
Title:

Circular RNA MAT2B Induces Colorectal Cancer Proliferation via Sponging miR-610, Resulting in an Increased E2F1 Expression.

Journal: Cancer Manag Res
Published: 2020/8/28
PubMed ID: 32848465