circRNA basic information
circBase ID: -
Name: hsa_circ_ZFR
Synonym: -
Host Gene: hsa-miR-578
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: BC cell lines (MCF7, BT-549, MDA-MB-231, MDA-MB-453)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HIF1A
Associated microRNA: hsa-miR-578
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

the silencing of circZFR suppressed BC malignant progression in vitro via the regulation of the miR-578/HIF1A axis, providing evidence for the crucial involvement of circZFR in BC pathogenesis.
Other information
Title:

CircZFR functions as a sponge of miR-578 to promote breast cancer progression by regulating HIF1A expression.

Journal: Cancer Cell Int
Published: 2020/8/25
PubMed ID: 32831653