circRNA basic information
circBase ID: hsa_circ_0000504
Name: hsa_circ_TUBGCP3
Synonym: -
Host Gene: hsa-miR-92a-3p, hsa-miR-485-5p, hsa-miR-520a-5p, hsa-miR-641
 
 
 
Disease basic information
DO ID:
9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: cell line
Sample type details: HCT116
circRNA-disease information
Detected method:
Q
M
Detected method confidence High
Expression pattern:
UP
Associated gene: -
Associated microRNA: hsa-miR-92a-3p, hsa-miR-485-5p, hsa-miR-520a-5p, hsa-miR-641
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
4
Description:

To validate the microarray data, four upregulated and four downregulated circRNAs were selected as representatives for further validation by qRT-PCR using primers mentioned in Table 1. According to the data in Figure 3, five of the eight tested circRNAs yielded results quite similar to those of microarray; these well-validated circRNAs included three upregulated circRNAs, hsa_circ_0007031, hsa_circ_0000504, and hsa_circ_0007006.

Other information
Title:

Microarray Analysis of Circular RNA Expression Profile Associated with 5-Fluorouracil-Based Chemoradiation Resistance in Colorectal Cancer Cells.

Journal: Biomed Res Int
Published: 2017/6/29
PubMed ID: 28656150