circRNA basic information
circBase ID: -
Name: hsa_circ_PSMC3
Synonym: CircPSMC3
Host Gene: hsa-miR-296-3p
 
 
 
Disease basic information
DO ID:
 229
DO name: female reproductive system disease
Disease details: Polycystic ovary syndrome
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: Human granulosa-like tumour cell lines (KGN, COV434, SVOG)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: PTEN
Associated microRNA: hsa-miR-296-3p
Biological function: inhibit cell proliferation and promote apoptosis by blocking the cell cycle
Molecular mechanism: -
Survival: through sponging miR-296-3p to regulate PTEN expression
Supported No.:
 1
Description:

we preliminarily characterized the role and possible insights of circPSMC3/miR-296-3p/PTEN axis in the proliferation and apoptosis of KGN cells
Other information
Title:

CircPSMC3 alleviates the symptoms of PCOS by sponging miR-296-3p and regulating PTEN expression.

Journal: J Cell Mol Med
Published: 2020/8/19
PubMed ID: 32808450