circRNA basic information
circBase ID: -
Name: hsa_circ_SMARCA5
Synonym: Circ-SMARCA5
Host Gene: hsa-miR-39-3p
 
 
 
Disease basic information
DO ID:
 9256
DO name: colorectal cancer
Disease details: colorectal cancer
Species: human
Species details: human
Sample type: tissue, cell line, PDX
Sample type details: human colorectal cell line (NCM460), CRC cell lines (SW480, HT29, SW620, Lovo)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: ARID4B
Associated microRNA: hsa-miR-39-3p
Biological function: inhibited CRC cell proliferation, migration and invasion
Molecular mechanism: downregulating hsa-miR-39-3p and upregulating ARID4B
Survival: -
Supported No.:
 1
Description:

Circ-SMARCA5 functions as a tumor suppressor by upregulating ARID4B expression via sponging miR-39-3p, and thereby inhibited CRC progression.
Other information
Title:

Circ-SMARCA5 suppresses colorectal cancer progression via downregulating miR-39-3p and upregulating ARID4B.

Journal: Dig Liver Dis
Published: 2020/8/19
PubMed ID: 32807692