circRNA basic information
circBase ID: hsa_circ_0029589
Name: hsa_circ_CHFR
Synonym: -
Host Gene: hsa-miR-214-3p
 
 
 
Disease basic information
DO ID:
 1936
DO name: atherosclerosis
Disease details: atherosclerosis
Species: human
Species details: human
Sample type: cell line
Sample type details: human aorta VSMCs
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: STIM1
Associated microRNA: hsa-miR-214-3p
Biological function: Hsa_circ_0029589 knockdown inhibits the proliferation, migration and invasion of vascular smooth muscle cells
Molecular mechanism: regulating hsa-miR-214-3p and STIM1
Survival: -
Supported No.:
 6
Description:

Circ_0029589 knockdown repressed proliferation, migration and invasion of VSMCs challenged via ox-LDL by regulating miR-214-3p and STIM1, indicating that circ_0029589 might play important role in atherosclerosis.
Other information
Title:

Hsa_circ_0029589 knockdown inhibits the proliferation, migration and invasion of vascular smooth muscle cells via regulating miR-214-3p and STIM1.

Journal: Life Sci
Published: 2020/8/17
PubMed ID: 32795540