circRNA basic information
circBase ID: -
Name: hsa_circ_RACGAP1
Synonym: -
Host Gene: hsa-miR-144-5p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: NSCLC cell lines (A549, Calu-3, H1299, H1975, PC-9)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
DN
Associated gene: CDKL1
Associated microRNA: hsa-miR-144-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

our study revealed a novel machinery of circRACGAP1/miR-144-5p/CDKL1 for the NSCLC tumorigenesis and development, providing potential diagnostic and therapeutic targets for NSCLC.
Other information
Title:

circRACGAP1 promotes non-small cell lung cancer proliferation by regulating miR-144-5p/CDKL1 signaling pathway.

Journal: Cancer Gene Ther
Published: 2020/8/12
PubMed ID: 32778770