circRNA basic information
circBase ID: -
Name: hsa_circ_MAGI3
Synonym: -
Host Gene: hsa-miR-515-5p
 
 
 
Disease basic information
DO ID:
 3908
DO name: lung non-small cell carcinoma
Disease details: non-small cell lung cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: NSCLC cell lines (H322, H460, A549, H1299), normal bronchial epithelial cells (NHBE)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HDGF
Associated microRNA: hsa-miR-515-5p
Biological function: accelerates the glycolysis
Molecular mechanism: through hsa-miR-515-5p/HDGF
Survival: poor
Supported No.:
 2
Description:

circMAGI3 promoted the glycolysis and proliferation of NSCLC cells. Mechanistically, circMAGI3 functioned as a sponge for miR-515-5p to relieve its target gene HDGF expression, thereby accelerating the glycolysis of NSCLC.
Other information
Title:

Circular RNA circMAGI3 accelerates the glycolysis of non-small cell lung cancer through miR-515-5p/HDGF.

Journal: Am J Transl Res
Published: 2020/8/11
PubMed ID: 32774748