circRNA basic information
circBase ID: hsa_circ_0061052
Name: hsa_circ_OSBPL2
Synonym: -
Host Gene: hsa-miR-515-5p
 
 
 
Disease basic information
DO ID:
 3083
DO name: chronic obstructive pulmonary disease
Disease details: chronic obstructive pulmonary disease
Species: human
Species details: human
Sample type: tissue
Sample type details: -
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: FoxC1/Snail pathway
Associated microRNA: hsa-miR-515-5p
Biological function: -
Molecular mechanism: miRNA sponge
Survival: -
Supported No.:
 2
Description:

by regulating miR-515-5p through a FoxC1/Snail regulatory axis, circ0061052 is involved in the CS-induced EMT and airway remodeling in COPD.
Other information
Title:

Circ0061052 regulation of FoxC1/Snail pathway via miR-515-5p is involved in the epithelial-mesenchymal transition of epithelial cells during cigarette smoke-induced airway remodeling.

Journal: Sci Total Environ
Published: 2020/8/10
PubMed ID: 32768781