circRNA basic information
circBase ID: hsa_circ_0000284
Name: hsa_circ_HIPK3
Synonym: -
Host Gene: hsa-miR-193a
 
 
 
Disease basic information
DO ID:
 1612
DO name: breast cancer
Disease details: breast cancer
Species: human
Species details: human
Sample type: tissue, cell line
Sample type details: normal breast cell line (MCF_10A), breast cancer cell lines (MCF_7, MDA_MB_231, MDA_MB_468, MDA_MB_453)
circRNA-disease information
Detected method:
Q
Detected method confidence High
Expression pattern:
UP
Associated gene: HMGB1/PI3K/AKT signaling
Associated microRNA: hsa-miR-193a
Biological function: facilitated cell proliferation, migration, and invasion
Molecular mechanism: regulated hsa-miR-193a/HMGB1/PI3K/AKT signaling
Survival: -
Supported No.:
 4
Description:

CirCHIPK3 regulated miR-193a/HMGB1/PI3K/AKT signaling to facilitate BC development and progression, providing a novel therapeutic target for BC.
Other information
Title:

Circular RNA CirCHIPK3 promotes cell proliferation and invasion of breast cancer by sponging miR-193a/HMGB1/PI3K/AKT axis.

Journal: Thorac Cancer
Published: 2020/8/9
PubMed ID: 32767499